CYP1A2 antibody (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2)

Details for Product anti-CYP1A2 Antibody No. ABIN6566470
Antigen
Reactivity
Mouse (Murine), Rat (Rattus)
164
65
41
Host
Rabbit
112
54
10
Clonality
Polyclonal
Conjugate
This CYP1A2 antibody is un-conjugated
10
6
5
3
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Western Blotting (WB)
133
64
59
45
24
20
13
9
4
4
4
2
2
2
1
Options
Immunogen Recombinant Protein of human CYP1A2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CYP1A2 (CYP1A2 Antibody Abstract)
Background

Synonyms: Aryl hydrocarbon hydroxylase,CP 12,CP12,CP1A2,CYP1A2,CYPIA2,Cytochrome P(3)450,Cytochrome P450 1A2,Cytochrome P450 4,Cytochrome P450 family 1 polypeptide 2,Cytochrome P450 family 1 subfamily A polypeptide 2,Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2,Cytochrome P450-P3,Cytochrome P4501A2,Dioxin inducable P3 450,Flavoprotein linked monooxygenase,Microsomal monooxygenase,P(3)450,P3 450,P450 4,P450 form 4,P450 P3,P450(PA),Xenobiotic monooxygenase

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Molecular Weight

Observed_MW: 55kDa

Calculated_MW: 58kDa

Gene ID 1544
UniProt P05177
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) antibody (ABIN6566470) Western blot analysis of extracts of various cell lines, using CYP1A2 antibody.