SOD1 antibody

Catalog No. ABIN6566553

The Rabbit Polyclonal anti-SOD1 antibody has been validated for WB. It is suitable to detect SOD1 in samples from Human, Mouse and Rat.

Quick Overview for SOD1 antibody (ABIN6566553)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOD1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SOD1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: SOD1

Background:

Synonyms: ALS,ALS1,Amyotrophic lateral sclerosis 1 adult,Cu/Zn SOD,Cu/Zn superoxide dismutase,Epididymis secretory protein Li 44,HEL S 44,Homodimer,hSod1,Indophenoloxidase A,IPOA,Mn superoxide dismutase,SOD,SOD soluble,SOD1,SOD2,SODC,SODC,Superoxide dismutase [Cu-Zn],Superoxide dismutase 1,Superoxide dismutase 1 soluble,Superoxide dismutase Cu Zn,Superoxide dismutase cystolic

Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Molecular Weight:

Observed_MW: 20kDa

Calculated_MW: 15kDa

Gene ID: 6647

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis