AKT2 antibody (V-Akt Murine Thymoma Viral Oncogene Homolog 2)

Details for Product anti-AKT2 Antibody No. ABIN6566577
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
436
207
170
55
55
51
50
49
46
45
45
45
28
18
4
3
2
1
1
Host
Rabbit
355
77
13
7
3
2
Clonality
Polyclonal
Conjugate
This AKT2 antibody is un-conjugated
25
24
21
19
19
17
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Western Blotting (WB)
382
266
171
85
64
44
38
26
26
21
19
12
8
6
4
3
1
1
Options
Immunogen A synthetic peptide of human AKT2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name AKT2 (AKT2 Antibody Abstract)
Background

Synonyms: Akt2,AKT2,HIHGHH,murine thymoma viral (v-akt) homolog-2,PKB,PKB beta,PKBB,PKBBETA,PRKBB,Protein kinase Akt 2,Protein kinase Akt-2,Protein kinase B beta,rac protein kinase beta,RAC-BETA,RAC-beta serine/threonine-protein kinase,RAC-PK-beta,v akt murine thymoma viral oncogene homolog 2

Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Molecular Weight

Observed_MW: 65kDa

Calculated_MW: 51kDa/55kDa

Gene ID 208
UniProt P31751
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) antibody (ABIN6566577) Western blot analysis of extracts of various cell lines, using AKT2 antibody.