Fatty Acid Synthase antibody

Catalog No. ABIN6566594

The Rabbit Polyclonal anti-Fatty Acid Synthase antibody is suitable to detect Fatty Acid Synthase in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for Fatty Acid Synthase antibody (ABIN6566594)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-Fatty Acid Synthase Antibody

Specificity: This antibody ist KO validated.

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human Fatty Acid Synthase (NP_004095.4).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: Fatty Acid Synthase

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Molecular Weight:

Observed_MW: 275kDa

Calculated_MW: 273kDa

Gene ID: 2194

UniProt: P49327

Pathways: AMPK Signaling