PAK1 antibody (P21-Activated Kinase 1)

Details for Product anti-PAK1 Antibody No. ABIN6566676
Antigen
Reactivity
Human, Rat (Rattus)
362
182
178
8
7
5
5
4
3
2
1
1
Host
Rabbit
341
15
7
1
Clonality
Polyclonal
Conjugate
This PAK1 antibody is un-conjugated
16
10
10
9
9
9
9
9
9
7
7
7
3
3
3
3
3
Application
Immunohistochemistry (IHC)
259
150
136
76
61
39
22
21
13
7
6
6
5
4
Options
Immunogen Recombinant protein of human PAK1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PAK1 (PAK1 Antibody Abstract)
Background

Synonyms: ADRB2,Alpha PAK,Alpha-PAK,MGC130000,MGC130001,p21 activated kinase 1,p21 protein (Cdc42/Rac) activated kinase 1,p21-activated kinase 1,p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related),p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog,yeast),p65 PAK,p65-PAK,P68-PAK,PAK alpha,PAK-1,Pak1,PAK1,Paka,PAKalpha,Protein kinase MUK2,Rac/p21-activated kinase,Serine/threonine-protein kinase PAK 1,STE20 homolog yeast

Background: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: Refer to figures

Calculated_MW: 60kDa/61kDa

Gene ID 5058
UniProt Q13153
Pathways MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
Application Notes IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-P21-Activated Kinase 1 (PAK1) antibody (ABIN6566676) Immunohistochemistry of paraffin-embedded rat kidney using PAK1 antibody.