PAK1 Products
(P21-Activated Kinase 1 (PAK1))
Categories
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
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Featured PAK1 Categories
PAK1 Antibodies
High quality antibodies with extensive validation data.
PAK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PAK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PAK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (6)
Cat. No.
ABIN2855705
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), IP
Validations
- (1)
- (7)
Cat. No.
ABIN562102
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7442222
Quantity
100 μL
Datasheet
Datasheet
Recommended PAK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380784
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380245
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593908
Quantity
96 tests
Datasheet
Datasheet
Recommended PAK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570583
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5569917
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570582
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PAK1 products
: "The metastatic promoter DEPDC1B induces epithelial-mesenchymal transition and promotes prostate cancer cell proliferation via Rac1-PAK1 signaling." in: Clinical and translational medicine, Vol. 10, Issue 6, pp. e191, (2020) (PubMed).: "Effect of Th9/IL-9 on the growth of gastric cancer in nude mice." in: OncoTargets and therapy, Vol. 12, pp. 2225-2234, (2019) (PubMed).
: "p21-activated kinase 1 activity is required for histone H3 Ser10 phosphorylation and chromatin condensation in mouse oocyte meiosis." in: Reproduction, fertility, and development, Vol. 29, Issue 7, pp. 1287-1296, (2018) (PubMed).
: "Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice." in: Cell death and differentiation, Vol. 23, Issue 1, pp. 169-81, (2016) (PubMed).
: "Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer." in: Molecular cancer, Vol. 13, pp. 201, (2014) (PubMed).
: "Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis." in: Cell reports, Vol. 9, Issue 4, pp. 1333-48, (2014) (PubMed).
: "SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic ? cells." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2527-34, (2013) (PubMed).
: "Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes." in: Journal of animal science and biotechnology, Vol. 4, Issue 1, pp. 13, (2013) (PubMed).
: "Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1709-22, (2013) (PubMed).
: "P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3025-35, (2013) (PubMed).
Synonyms and alternative names related to PAK1
p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S), p21 (RAC1) activated kinase 1 (PAK1), p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), p21 (RAC1) activated kinase 1 (Pak1), Serine/threonine-protein kinase pak-1 (pak-1), AW045634, pak, pak-1, PAK-1, Paka, pakalpha, PAKalpha, X-PAK1, XPak1Protein level used designations for PAK1
- p21 GTPase-associated kinase 1
- p21-activated kinase 1
- p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
- putative CDKN1A-activated kinase 1
- STE20 homolog, yeast
- alpha-PAK
- p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
- p65-PAK
- serine/threonine-protein kinase PAK 1
- CDC42/RAC effector kinase PAK-A
- activated protein kinase alpha
- PAK-1
- p21 (CDKN1A)-activated kinase 1
- p68-PAK
- protein kinase MUK2
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