TLR7 antibody

Catalog No. ABIN6566727

This anti-TLR7 antibody is a Rabbit Polyclonal antibody detecting TLR7 in IHC and IF. Suitable for Human and Mouse.

Quick Overview for TLR7 antibody (ABIN6566727)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TLR7 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human TLR7

Isotype: IgG

Application Details

Application Notes: IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7

Background:

Synonyms: PRO285,TLR 7,Tlr7,TLR7,Toll like receptor 7,Toll-like receptor 7,UNQ248

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Molecular Weight:

Calculated_MW: 120kDa

Gene ID: 51284

UniProt: Q9NYK1

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades