ATP1B3 antibody (C-Term)

Catalog No. ABIN656673

Cited in 1 publication. The Rabbit Polyclonal anti-ATP1B3 antibody (Clone RB32424) (ABIN656673) specifically detects ATP1B3 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ATP1B3 antibody (C-Term) (ABIN656673)

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1B3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32424

Product Details anti-ATP1B3 Antibody

Binding Specificity: AA 241-270, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-270 amino acids from the C-terminal region of human ATP1B3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ATP1B3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-ATP1B3 antibody (ABIN656673)

Wang, Wu, Zhou, Guo, Zheng, Wang, Bi, Liu, Zhou, Guo, Sha: "Mapping of the N-linked glycoproteome of human spermatozoa." in: Journal of proteome research, Vol. 12, Issue 12, pp. 5750-9, (2013) (PubMed).

Target Details for ATP1B3

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Alternative Name: ATP1B3

Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq].

Molecular Weight: 31513

Gene ID: 483

NCBI Accession: NP_001670

UniProt: P54709

Pathways: Thyroid Hormone Synthesis