IL17RA antibody

Catalog No. ABIN6566759

The Rabbit Polyclonal anti-IL17RA antibody is suitable to detect IL17RA in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for IL17RA antibody (ABIN6566759)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL17RA Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human IL17RA

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL17RA

Background:

Synonyms: CANDF5,CD217,CD217 antigen,CDw217,CTLA8,HIL 17R,hIL17R,I17RA,IL 17 receptor A,IL 17 receptor,IL 17RA,IL-17 receptor A,IL-17RA,IL17,IL17A receptor,IL17R,IL17RA,IMD51,Interleukin 17 receptor A,Interleukin-17 receptor A,MGC10262

Background: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 92kDa/96kDa

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome