LILRB2 antibody

Catalog No. ABIN6566787

This Rabbit Polyclonal antibody specifically detects LILRB2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LILRB2 antibody (ABIN6566787)

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LILRB2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human LILRB2

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LILRB2

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Alternative Name: CD85d

Background:

Synonyms: CD85 antigen-like family member D,CD85d,CD85d antigen,ILT 4,ILT-4,ILT4,Immunoglobulin like transcript 4,Immunoglobulin-like transcript 4,Leukocyte immunoglobulin like receptor 2,Leukocyte immunoglobulin like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,Leukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 2,LILRA6,LILRB2,LIR 2,LIR-2,LIR2,LIRb,LIRB2,MIR 10,MIR-10,MIR10,Monocyte/macrophage immunoglobulin like receptor 10,Monocyte/macrophage immunoglobulin-like receptor 10

Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 65kDa

Calculated_MW: 51kDa/55kDa/64kDa/65kDa

Gene ID: 10288

UniProt: Q8N423

Pathways: Cellular Response to Molecule of Bacterial Origin