LOXL1 antibody

Catalog No. ABIN6566806

The Rabbit Polyclonal anti-LOXL1 antibody has been validated for IF. It is suitable to detect LOXL1 in samples from Human, Mouse and Rat.

Quick Overview for LOXL1 antibody (ABIN6566806)

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-LOXL1 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human LOXL1 (NP_005567.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Alternative Name: LOXL1

Background: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 63kDa

Gene ID: 4016

UniProt: Q08397