Envoplakin antibody

Catalog No. ABIN6566815

This anti-Envoplakin antibody is a Rabbit Polyclonal antibody detecting Envoplakin in WB. Suitable for Human, Mouse and Rat.

Quick Overview for Envoplakin antibody (ABIN6566815)

Target: Envoplakin (EVPL)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Envoplakin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Envoplakin Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human EVPL

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Envoplakin

Target: Envoplakin (EVPL)

Alternative Name: EVPL

Background:

Synonyms: 210 kDa cornified envelope,210 kDa cornified envelope precursor protein,210 kDa paraneoplastic pemphigus antigen,EVPK,P210

Background: This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.

Molecular Weight:

Observed_MW: 270kDa

Calculated_MW: 231kDa

Gene ID: 2125

UniProt: Q92817