EIF2B3 antibody

Catalog No. ABIN6566842

This anti-EIF2B3 antibody is a Rabbit Polyclonal antibody detecting EIF2B3 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for EIF2B3 antibody (ABIN6566842)

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF2B3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human EIF2B3

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EIF2B3

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Alternative Name: EIF2B gamma

Background:

Synonyms: EI2BG,EIF 2B,eIF 2B GDP GTP exchange factor subunit gamma,eIF-2B GDP-GTP exchange factor subunit gamma,eIF2B-gamma,Eif2b3,EIF2Bgamma,Eukaryotic translation initiation factor 2B subunit 3 gamma,Eukaryotic translation initiation factor 2B,gamma,eukaryotic translation initiation factor 2B,subunit 3 gamma,58  kDa,OTTHUMP00000010262,OTTHUMP00000010263,Translation initiation factor eIF-2B subunit gamma

Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 50kDa

Calculated_MW: 44kDa/46kDa/50kDa

Gene ID: 8891

UniProt: Q9NR50