LMAN1 antibody

Catalog No. ABIN6566931

The Rabbit Polyclonal anti-LMAN1 antibody has been validated for WB. It is suitable to detect LMAN1 in samples from Human, Mouse and Rat.

Quick Overview for LMAN1 antibody (ABIN6566931)

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMAN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LMAN1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human LMAN1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Alternative Name: LMAN1

Background:

Synonyms: Endoplasmic reticulum golgi intermediate compartment protein 53 ,ER-Golgi intermediate compartment 53 kDa protein,ERGIC-53,ERGIC53,ERGIC53 like protein,F5F8D,FMFD1,Gp58,Intracellular mannose specific lectin ,Intracellular mannose-specific lectin MR60,Lectin mannose binding 1 ,Lectin mannose-binding 1,Lman1,LMAN1 like protein ,LMAN1,MCFD1,MR60,Protein ERGIC-53

Background: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and  pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.

Molecular Weight:

Observed_MW: 55kDa

Calculated_MW: 57kDa

Gene ID: 3998

UniProt: P49257