P4HA1 antibody

Catalog No. ABIN6566970

This anti-P4HA1 antibody is a Rabbit Polyclonal antibody detecting P4HA1 in WB. Suitable for Human.

Quick Overview for P4HA1 antibody (ABIN6566970)

Target: P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P4HA1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human P4HA1

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P4HA1

Target: P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))

Alternative Name: P4HA1

Background:

Synonyms: 2-oxoglutarate-4-dioxygenase subunit alpha-1,4-hydroxylase,alpha I subunit,4-PH alpha-1,P4HA,P4HA1,P4HA1,Procollagen-proline,Procollagen-proline,2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase),alpha polypeptide I,Prolyl 4-hydroxylase subunit alpha-1

Background: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight:

Observed_MW: 60kDa

Calculated_MW: 58kDa/60kDa/61kDa

Gene ID: 5033

UniProt: P13674