BDNF antibody (Brain-Derived Neurotrophic Factor)

Details for Product anti-BDNF Antibody No. ABIN6567050
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
This BDNF antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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Options
Immunogen Recombinant protein of human BDNF
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name BDNF (BDNF Antibody Abstract)
Background

Synonyms: Abrineurin,ANON2,BDNF,BDNF,Brain Derived Neurotrophic Factor,Brain-derived neurotrophic factor,BULN2,MGC34632,Neurotrophin

Background: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

Molecular Weight

Calculated_MW: 27kDa/28kDa/29kDa/31kDa/37kDa

Gene ID 627
UniProt P23560
Pathways RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
Application Notes IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Brain-Derived Neurotrophic Factor (BDNF) antibody (ABIN6567050) Immunohistochemistry of paraffin-embedded rat brain using BDNF antibody.