FAK antibody (PTK2 Protein tyrosine Kinase 2)

Details for Product anti-PTK2 Antibody No. ABIN6567085
Antigen
Reactivity
Human
779
545
523
42
28
23
15
9
9
8
8
4
3
3
3
3
3
2
1
1
Host
Rabbit
729
77
3
2
1
1
Clonality
Polyclonal
Conjugate
This FAK antibody is un-conjugated
30
23
23
23
23
22
22
17
17
11
11
11
11
11
5
2
2
1
Application
Western Blotting (WB)
537
253
194
145
140
104
58
35
29
14
9
6
3
3
2
Options
Immunogen A synthetic peptide of human PTK2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name FAK (PTK2 Antibody Abstract)
Background

Synonyms: FADK 1,FADK,FAK related non kinase polypeptide,FAK1,FAK1,Focal adhesion kinase 1,Focal adhesion Kinase,Focal adhesion kinase isoform FAK Del33,Focal adhesion kinase related nonkinase,FRNK,p125FAK,pp125FAK,PPP1R71,Protein phosphatase 1 regulatory subunit 71,Protein tyrosine kinase 2,Protein-tyrosine kinase 2,Ptk2,PTK2 protein tyrosine kinase 2

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 119kDa

Calculated_MW: 39kDa/48kDa/63kDa/99kDa/114kDa/119kDa/120kDa

Gene ID 5747
UniProt Q05397
Pathways Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody (ABIN6567085) Western blot analysis of extracts of various cell lines, using PTK2 antibody.