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FAK antibody (PTK2 Protein tyrosine Kinase 2) (AA 396-423) Primary Antibody

PTK2 Reactivity: Human FACS, IF, IHC (p), WB Host: Rabbit Polyclonal RB20775 unconjugated
Pubmed (2)
Catalog No. ABIN1882121
$412.50
Plus shipping costs $45.00
400 μL ABIN1882121
400 μL ABIN1882121
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days
  • Target
    FAK (PTK2)
    Binding Specificity
    • 37
    • 29
    • 28
    • 25
    • 24
    • 24
    • 19
    • 17
    • 17
    • 16
    • 15
    • 15
    • 14
    • 10
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 396-423
    Reactivity
    • 347
    • 299
    • 255
    • 31
    • 22
    • 20
    • 18
    • 13
    • 8
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 350
    • 31
    • 3
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 347
    • 41
    Polyclonal
    Conjugate
    • 198
    • 24
    • 17
    • 15
    • 14
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 1
    This FAK antibody is un-conjugated
    Application
    • 228
    • 136
    • 121
    • 107
    • 99
    • 79
    • 65
    • 49
    • 35
    • 28
    • 26
    • 7
    • 4
    • 3
    • 2
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    C, M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human PTK2.
    Clone
    RB20775
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Stowe, Turlings, Loughrin, Lewis, Tumlinson: "The chemistry of eavesdropping, alarm, and deceit." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 1, pp. 23-8, 1995 (PubMed).

    Calalb, Polte, Hanks: "Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases." in: Molecular and cellular biology, Vol. 15, Issue 2, pp. 954-63, 1995 (PubMed).

  • Target
    FAK (PTK2)
    Alternative Name
    PTK2 (PTK2 Antibody Abstract)
    Synonyms
    FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, PTK2, Fadk, mKIAA4203, fak, fak1a, ptk2, ptk2a, wu:fa18c04, zgc:66114, CG10023, CT28129, DFAK, DFak, DFak56, Dfak, Dfak56, DmFAK, Dmel\\CG10023, Fak56, Fak56D, fak56, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, PTK2 protein tyrosine kinase 2, protein tyrosine kinase 2ab, Focal adhesion kinase, PTK2, ptk2.L, Ptk2, ptk2ab, Fak
    Background
    PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
    Molecular Weight
    119233
    NCBI Accession
    NP_001186578, NP_722560
    UniProt
    Q05397
    Pathways
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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