FAK antibody (AA 355-490)
Quick Overview for FAK antibody (AA 355-490) (ABIN562519)
Target
See all FAK (PTK2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 355-490
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Purpose
- Mouse monoclonal antibody raised against a partial recombinant PTK2.
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Sequence
- EGFYPSPQHM VQTNHYQVSG YPGSHGITAM AGSIYPGQAS LLDQTDSWNH RPQEIAMWQP NVEDSTVLDL RGIGQVLPTH LMEERLIRQQ QEMEEDQRWL EKEERFLKPD VRLSRGSIDR EDGSLQGPIG NQHIYQ
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Cross-Reactivity
- Human
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Characteristics
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- PTK2 (AAH28733, 355 a.a. ~ 490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- In 1x PBS, pH 7.4
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5472-8, (2010) (PubMed).
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- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
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Alternative Name
- PTK2
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Background
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Full Gene Name: PTK2 protein tyrosine kinase 2
Synonyms: FADK,FAK,FAK1,pp125FAK -
Gene ID
- 5747
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Pathways
- Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Target
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