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FAK antibody (PTK2 Protein tyrosine Kinase 2) (AA 821-848) Primary Antibody

PTK2 Reactivity: Human FACS, IF, IHC (p), WB Host: Rabbit Polyclonal RB20776 unconjugated
Pubmed (1)
Catalog No. ABIN652554
$423.50
Plus shipping costs $45.00
400 μL ABIN652554
400 μL ABIN652554
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days
  • Target
    FAK (PTK2)
    Binding Specificity
    • 37
    • 29
    • 28
    • 25
    • 24
    • 24
    • 19
    • 17
    • 17
    • 16
    • 15
    • 15
    • 13
    • 10
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 821-848, C-Term
    Reactivity
    • 347
    • 299
    • 255
    • 31
    • 22
    • 20
    • 18
    • 13
    • 8
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 350
    • 31
    • 3
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 347
    • 41
    Polyclonal
    Conjugate
    • 198
    • 24
    • 17
    • 15
    • 14
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 1
    This FAK antibody is un-conjugated
    Application
    • 228
    • 136
    • 121
    • 107
    • 99
    • 79
    • 65
    • 49
    • 35
    • 28
    • 26
    • 7
    • 4
    • 3
    • 2
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-848 amino acids from the C-terminal region of human PTK2.
    Clone
    RB20776
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Ma, He, Zhang, Fei, Niu, Wang, Ding, Xu, Chen, Zhu: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, 2012 (PubMed). Method employed by authors: Western Blotting (WB)

  • Target
    FAK (PTK2)
    Alternative Name
    PTK2 (PTK2 Antibody Abstract)
    Synonyms
    FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, PTK2, Fadk, mKIAA4203, fak, fak1a, ptk2, ptk2a, wu:fa18c04, zgc:66114, CG10023, CT28129, DFAK, DFak, DFak56, Dfak, Dfak56, DmFAK, Dmel\\CG10023, Fak56, Fak56D, fak56, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, PTK2 protein tyrosine kinase 2, protein tyrosine kinase 2ab, Focal adhesion kinase, PTK2, ptk2.L, Ptk2, ptk2ab, Fak
    Background
    PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
    Molecular Weight
    119233
    Gene ID
    5747
    NCBI Accession
    NP_001186578, NP_722560
    UniProt
    Q05397
    Pathways
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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