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FAK antibody (C-Term)

Name: FAK antibody (C-Term)
SKU: ABIN652554
Price: 429 USD
Availability: InStock

PTK2 Reactivity: Human WB, IHC (p), IF, FACS Host: Rabbit Polyclonal RB20776 unconjugated

Western blot analysis of PTK2 (arrow) using rabbit polyclonal PTK2 Antibody (C-term) (ABIN652554 and ABIN2842372). (FAK antibody (C-Term))

PTK2 Antibody (C-term) (ABIN652554 and ABIN2842372) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram). (FAK antibody (C-Term))

FACS

Confocal immunofluorescent analysis of PTK2 Antibody (C-term) (ABIN652554 and ABIN2842372) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (FAK antibody (C-Term))

Formalin-fixed and paraffin-embedded human brain tissue reacted with PTK2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (FAK antibody (C-Term))

IHC (p)

4 images

(1 reference)

Catalog No. ABIN652554

Datasheet as PDF

Target See all FAK (PTK2) Antibodies

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
Binding Specificity
37

29

27

25

23

23

18

18

16

16

12

11

8

7

6

6

5

5

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 821-848, C-Term
Reactivity
325

285

220

22

21

18

17

12

9

7

6

5

3

3

3

2

1

1

1

1
Human
Host
337

18

3

2

1

1
Rabbit
Compatible Secondaries
Clonality
327

35
Polyclonal
Conjugate
178

19

16

13

13

13

13

13

13

13

10

9

9

9

9

9

2

1
This FAK antibody is un-conjugated
Application
298

126

122

121

107

74

68

51

31

30

25

5

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Predicted Reactivity

M, Rat

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 821-848 amino acids from the C-terminal region of human PTK2.

Clone

RB20776

Isotype

Ig Fraction

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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr397) antibody
PTK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 700-800) antibody
PTK2 Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 798-1041) antibody
PTK2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr576) antibody
PTK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 396-423) antibody
PTK2 Reactivity: Human WB, IHC (p), IF, FACS Host: Rabbit Polyclonal RB20775 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 355-490) antibody
PTK2 Reactivity: Human WB, ELISA, IP, PLA Host: Mouse Monoclonal 2C3 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr861) antibody
PTK2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reactivity: Human WB, ELISA, FACS, ICC Host: Mouse Monoclonal 10H7E9 unconjugated

Application Notes

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Ma, He, Zhang, Fei, Niu, Wang, Ding, Xu, Chen, Zhu: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).
Target

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name

PTK2 (PTK2 Products)

Synonyms

FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody

Background

PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

Molecular Weight

119233

Gene ID

5747

NCBI Accession

NP_001186578, NP_722560

UniProt

Q05397

Pathways

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling