LC3B antibody

Catalog No. ABIN6567107

The Rabbit Polyclonal anti-LC3B antibody is suitable to detect LC3B in samples from Human, Mouse, Rat and Pig. It has been validated for WB, IHC and IF.

Quick Overview for LC3B antibody (ABIN6567107)

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LC3B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LC3B Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human MAP1LC3B

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Alternative Name: MAP1LC3B

Background:

Synonyms: ATG8F,Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,LC3B,LC3II,MAP1 light chain 3 like protein 2,MAP1 light chain 3-like protein 2,MAP1A/1BLC3,MAP1A/MAP1B LC3 B,MAP1A/MAP1B light chain 3 B,MAP1ALC3,MAP1LC3B a,Map1lc3b,Microtubule associated protein 1 light chain 3 beta,Microtubule-associated protein 1 light chain 3 beta,Microtubule-associated proteins 1A/1B light chain 3B,MLP3B

Background: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Molecular Weight:

Observed_MW: 14kDa, 16kDa

Calculated_MW: 14kDa

Gene ID: 81631

UniProt: Q9GZQ8

Pathways: Autophagy