LSD1 antibody

Catalog No. ABIN6567175

This Rabbit Polyclonal antibody specifically detects LSD1 in WB, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LSD1 antibody (ABIN6567175)

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-LSD1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human KDM1A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Alternative Name: KDM1A

Background:

Synonyms: Amine oxidase (flavin containing) domain 2,Amine oxidase,flavin containing,2,AOF2,BHC110,BRAF35 HDAC complex protein BHC110,BRAF35-HDAC complex protein BHC110,BRAF35/HDAC complex,110-kD subunit,CPRF,EC1,FAD binding protein BRAF35 HDAC complex,110 kDa subunit,Flavin-containing amine oxidase domain-containing protein 2,KDM 1,KDM1,Kdm1a,KDM1A,KIAA0601,LSD 1,LSD1,Lysine (K) specific demethylase 1,Lysine (K) specific demethylase 1A,Lysine demethylase 1A,Lysine specific histone demethylase 1,Lysine specific histone demethylase 1A,Lysine-specific demethylase 1,Lysine-specific demethylase 1A,Lysine-specific histone demethylase 1A

Background: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 96-117kDa

Calculated_MW: 92kDa/95kDa

Gene ID: 23028

UniProt: O60341

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect