LSD1 antibody

Catalog No. ABIN6567175

This Rabbit Polyclonal antibody specifically detects LSD1 in WB, IF, IP. It exhibits reactivity toward Human, Mouse, Rat.

Quick Overview for LSD1 antibody (ABIN6567175)

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-LSD1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human KDM1A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Alternative Name: KDM1A

Background:

Synonyms: Amine oxidase (flavin containing) domain 2,Amine oxidase,flavin containing,2,AOF2,BHC110,BRAF35 HDAC complex protein BHC110,BRAF35-HDAC complex protein BHC110,BRAF35/HDAC complex,110-kD subunit,CPRF,EC1,FAD binding protein BRAF35 HDAC complex,110 kDa subunit,Flavin-containing amine oxidase domain-containing protein 2,KDM 1,KDM1,Kdm1a,KDM1A,KIAA0601,LSD 1,LSD1,Lysine (K) specific demethylase 1,Lysine (K) specific demethylase 1A,Lysine demethylase 1A,Lysine specific histone demethylase 1,Lysine specific histone demethylase 1A,Lysine-specific demethylase 1,Lysine-specific demethylase 1A,Lysine-specific histone demethylase 1A

Background: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 96-117kDa

Calculated_MW: 92kDa/95kDa

Gene ID: 23028

UniProt: O60341

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect