Glutamate Receptor 3 antibody

Catalog No. ABIN6567185

This anti-Glutamate Receptor 3 antibody is a Rabbit Polyclonal antibody detecting Glutamate Receptor 3 in WB and IF. Suitable for Human, Rat and Mouse.

Quick Overview for Glutamate Receptor 3 antibody (ABIN6567185)

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Glutamate Receptor 3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human GRIA3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: GRIA3

Background:

Synonyms: AMPA 3,AMPA selective glutamate receptor 3,AMPA-selective glutamate receptor 3,dJ1171F9.1,GluA3,GLUK3,GluR 3,GLUR C,GLUR K3,GluR-3,GluR-C,GluR-K3,GLUR3,GLURC,Glutamate ionotropic receptor AMPA type subunit 3,Glutamate receptor 3,Glutamate receptor C,Glutamate receptor ionotrophic AMPA 3,Glutamate receptor ionotropic,Glutamate receptor subunit 3,Glutamate receptor,ionotropic,AMPA 3,GRIA 3,Gria3,GRIA3,Ionotrophic Glutamate Receptor,MRX94

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Molecular Weight:

Observed_MW: 101kDa

Calculated_MW: 101kDa

Gene ID: 2892

UniProt: P42263

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane