SEC62 antibody (N-Term)

Catalog No. ABIN656777

The Rabbit Polyclonal anti-SEC62 antibody is suitable to detect SEC62 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for SEC62 antibody (N-Term) (ABIN656777)

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC62 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32610

Product Details anti-SEC62 Antibody

Binding Specificity: AA 1-30, N-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SEC62 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Alternative Name: SEC62

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Molecular Weight: 45862

Gene ID: 7095

NCBI Accession: NP_003253

UniProt: Q99442