Asialoglycoprotein Receptor 2 antibody

Catalog No. ABIN6568218

Product Details anti-Asialoglycoprotein Receptor 2 Antibody

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ASGR2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Alternative Name: ASGR2 (ASGR2 Products)

Background:

Synonyms: ASGP R,ASGP-R 2,ASGPR 2,ASGPR2,Asgr2,ASGR2,Asialoglycoprotein receptor 2,C type lectin domain family 4 member H2,C-type lectin domain family 4 member H2,CLEC4H2,HBxAg-binding protein,HBXBP,Hepatic lectin 2,Hepatic lectin H2,Hepatic lectin R2/3,HL-2,Hs.1259,L H2,LH2 ,MGC108546,MHL 2 ,RHL2

Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight:

Observed_MW: 38kDa

Calculated_MW: 32kDa/35kDa

Gene ID: 433

UniProt: P07307

Pathways: Thyroid Hormone Synthesis