MTRR antibody

Catalog No. ABIN6568413

This Rabbit Polyclonal antibody specifically detects MTRR in WB. It exhibits reactivity toward Human.

Quick Overview for MTRR antibody (ABIN6568413)

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTRR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTRR Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human MTRR

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTRR

Target: MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))

Alternative Name: MTRR

Background:

Synonyms: [methionine synthase] cobalamin methyltransferase (cob(II)alamin reducing) ,5 methyltetrahydrofolate homocysteine methyltransferase reductase,cblE,Methionine synthase reductase,Methionine synthase reductase, mitochondrial,MGC129643,MSR

Background: This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 6kDa/77kDa/80kDa

Gene ID: 4552

UniProt: Q9UBK8

Pathways: Methionine Biosynthetic Process