OXT antibody

Catalog No. ABIN6568634

Product Details anti-OXT Antibody

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXT antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human OXT

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Alternative Name: OXT (OXT Products)

Background:

Synonyms: MGC126890,MGC126892,Neurophysin 1 ,Neurophysin I,Ocytocin,OT,OT NPI,OXT,Oxytocin Neurophysin preproprotein,Oxytocin prepro (neurophysin I),Oxytocin prepropeptide,Oxytocin-neurophysin 1

Background: This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.

Molecular Weight:

Observed_MW: 13kDa

Calculated_MW: 12kDa

Gene ID: 5020

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour