OXT antibody (AA 1-125)
Quick Overview for OXT antibody (AA 1-125) (ABIN7269141)
Target
See all OXT AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-125
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Purpose
- OXT Rabbit pAb
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Sequence
- MAGPSLACCL LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA EELGCFVGTA EALRCQEENY LPSPCQSGQK ACGSGGRCAV LGLCCSPDGC HADPACDAEA TFSQR
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human OXT (NP_000906.1).
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Isotype
- IgG
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Application Notes
- WB,1:200 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- OXT (Oxytocin, Prepropeptide (OXT))
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Alternative Name
- OXT
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Background
- This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.,OXT,OT,OT-NPI,OXT-NPI,Neuroscience,OXT
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Molecular Weight
- 12kDa
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Gene ID
- 5020
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UniProt
- P01178
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Pathways
- Myometrial Relaxation and Contraction, Feeding Behaviour
Target
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