Plakophilin 2 antibody (C-Term)

Catalog No. ABIN656864

The Rabbit Polyclonal anti-Plakophilin 2 antibody has been validated for WB and IHC (p). It is suitable to detect Plakophilin 2 in samples from Human.

Quick Overview for Plakophilin 2 antibody (C-Term) (ABIN656864)

Target: Plakophilin 2 (PKP2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB30230

Product Details anti-Plakophilin 2 Antibody

Binding Specificity: AA 838-866, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PKP2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PKP2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for Plakophilin 2

Target: Plakophilin 2 (PKP2)

Alternative Name: PKP2

Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Molecular Weight: 97415

Gene ID: 5318

NCBI Accession: NP_001005242, NP_004563

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection