PMS1 antibody

Catalog No. ABIN6569165

Product Details anti-PMS1 Antibody

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PMS1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Alternative Name: PMS1 (PMS1 Products)

Background:

Synonyms: DNA mismatch repair protein PMS1,FLJ98259,HNPCC3,hPMS1,Human homolog of yeast mutL,Mismatch repair gene PMSL1,pms1,PMS1 postmeiotic segregation increased 1 (S. cerevisiae),PMS1 postmeiotic segregation increased 1,PMS1 protein homolog 1,PMS1,PMSL1,Rhabdomyosarcoma antigen MU RMS 40.10B,Rhabdomyosarcoma antigen MU RMS 40.10E

Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Molecular Weight:

Observed_MW: 65kDa

Calculated_MW: 62kDa/86kDa/101kDa/105kDa

Gene ID: 5378

UniProt: P54277