Dynamin 1-Like antibody
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- Target See all Dynamin 1-Like (DNM1L) Antibodies
- Dynamin 1-Like (DNM1L)
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dynamin 1-Like antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human DNM1L
- Isotype
- IgG
- Top Product
- Discover our top product DNM1L Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Dynamin 1-Like (DNM1L)
- Alternative Name
- DRP1 (DNM1L Products)
- Background
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Synonyms: DLP1,dnm1l,DNM1L,Dnm1p/Vps1p-like protein,dnml1,DRP1,DVLP,Dymple,Dynamin 1 like,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin like protein,Dynamin related protein 1,Dynamin-1-like protein,Dynamin-like protein 4,Dynamin-like protein,Dynamin-like protein IV,Dynamin-related protein 1,DYNIV 11,EMPF,EMPF1,FLJ41912,HdynIV,VPS1
Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
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Observed_MW: 78-82kDa
Calculated_MW: 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa
- Gene ID
- 10059
- UniProt
- O00429
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