Dynamin 1-Like antibody (AA 411-710)

Catalog No. ABIN3023670

Product Details anti-Dynamin 1-Like Antibody

Target: Dynamin 1-Like (DNM1L)

Binding Specificity: AA 411-710

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1-Like antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 411-710 of human DRP1 (NP_036193.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DNM1L (DNM1L Products)

Synonyms: DLP1 antibody, DRP1 antibody, DVLP antibody, DYMPLE antibody, EMPF antibody, HDYNIV antibody, 6330417M19Rik antibody, AI450666 antibody, Dlp1 antibody, Dnmlp1 antibody, Drp1 antibody, python antibody, Dnml1 antibody, dnm1l antibody, MGC53850 antibody, zgc:66163 antibody, DNM1L antibody, 18.m06247 antibody, CG3210 antibody, DRP antibody, Dmel\CG3210 antibody, Dnm1/Drp1 antibody, Drp antibody, Drp-1 antibody, drp-1 antibody, drp1 antibody, frat antibody, l(2)22Fc antibody, l(2)22Fd antibody, l(2)ND2 antibody, l(2)ND3 antibody, dynamin 1 like antibody, dynamin 1-like antibody, dynamin 1-like L homeolog antibody, dynamin-1-like antibody, dynamin-1-like protein antibody, dynamin-like protein antibody, Dynamin related protein 1 antibody, DNM1L antibody, Dnm1l antibody, dnm1l.L antibody, dnm1l antibody, LOC100369408 antibody, LOC411472 antibody, dyn1 antibody, cgd1_580 antibody, EHI_052740 antibody, PVX_092875 antibody, BBOV_II002980 antibody, Drp1 antibody

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.,DNM1L,DLP1,DRP1,DVLP,DYMPLE,EMPF,EMPF1,HDYNIV,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,DNM1L

Molecular Weight: 60 kDa/78 kDa/79 kDa/80 kDa/81 kDa/82 kDa/83 kDa

Gene ID: 10059

UniProt: O00429