G3BP1 antibody

Catalog No. ABIN6569853

This Rabbit Polyclonal antibody specifically detects G3BP1 in WB and IF. It exhibits reactivity toward Human, Mouse and Duck.

Quick Overview for G3BP1 antibody (ABIN6569853)

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Reactivity: Human, Mouse, Duck

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G3BP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-G3BP1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human G3BP1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for G3BP1

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Alternative Name: G3BP1

Background:

Synonyms: ATP dependent DNA helicase VIII,ATP-dependent DNA helicase VIII,G3BP,G3BP stress granule assembly factor 1,G3BP-1,G3bp1,G3BP1,GAP binding protein,GAP SH3 domain binding protein 1,GAP SH3 domain-binding protein 1,GTPase activating protein (SH3 domain) binding protein 1,hDH VIII,Human DNA helicase VIII,MGC111040,Ras GTPase activating protein binding protein 1,Ras GTPase activating protein SH3 domain binding protein,Ras GTPase-activating protein-binding protein 1,RasGAP associated endoribonuclease G3BP

Background: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Molecular Weight:

Observed_MW: 64kDa

Calculated_MW: 13kDa/52kDa

Gene ID: 10146

UniProt: Q13283

Pathways: SARS-CoV-2 Protein Interactome