PYDC1 antibody (AA 13-42)

Catalog No. ABIN657048

Product Details anti-PYDC1 Antibody

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Binding Specificity: AA 13-42

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PYDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the Central region of human PYDC1.

Clone: RB32352

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PYDC1

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Alternative Name: PYDC1 (PYDC1 Products)

Synonyms: ASC2 antibody, POP1 antibody, PYC1 antibody, pyrin domain containing 1 antibody, PYDC1 antibody

Background: PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Molecular Weight: 10107

NCBI Accession: NP_690865

UniProt: Q8WXC3