CD320 antibody (C-Term)

Catalog No. ABIN657061

This Rabbit Polyclonal antibody specifically detects CD320 in WB. It exhibits reactivity toward Human.

Quick Overview for CD320 antibody (C-Term) (ABIN657061)

Target: CD320 (CD320 Molecule (CD320))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD320 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32506

Product Details anti-CD320 Antibody

Binding Specificity: AA 153-182, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for CD320

Target: CD320 (CD320 Molecule (CD320))

Alternative Name: CD320

Background: The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2, MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30 % of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).

Molecular Weight: 28991

NCBI Accession: NP_001159367, NP_057663

UniProt: Q9NPF0