ERCC4 antibody

Catalog No. ABIN6571574

This Rabbit Polyclonal antibody specifically detects ERCC4 in WB and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ERCC4 antibody (ABIN6571574)

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-ERCC4 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ERCC4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IP 1:20 - 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERCC4

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Alternative Name: ERCC4

Background:

Synonyms: DNA excision repair protein ERCC 4,DNA excision repair protein ERCC-4,DNA excision repair protein ERCC4,DNA repair endonuclease XPF,DNA repair protein complementing XP F cells,DNA repair protein complementing XP-F cells,ERCC 11,ERCC 4,ERCC11,ERCC4,Excision repair complementing defective in Chinese hamster,Excision repair cross complementing rodent repair deficiency complementation group 4,excision repair cross-complementation group 4,FANCQ,RAD 1,RAD1,Xeroderma pigmentosum complementation group F,Xeroderma pigmentosum group F complementing protein,Xeroderma pigmentosum group F-complementing protein,Xeroderma pigmentosum VI,XP,group G,XP6,XPF

Background: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Molecular Weight:

Observed_MW: 120kDa

Calculated_MW: 42kDa/104kDa

Gene ID: 2072

UniProt: Q92889

Pathways: DNA Damage Repair