RGS20 antibody

Catalog No. ABIN6571601

This Rabbit Polyclonal antibody specifically detects RGS20 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RGS20 antibody (ABIN6571601)

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS20 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human RGS20

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20

Background:

Synonyms: G(z)GAP,Gz selective GTPase activating protein,Gz-GAP,Gz-selective GTPase-activating protein,HGNC:14600,Regulator of G protein signaling 20,Regulator of G-protein signaling 20,Regulator of G-protein signaling Z1,Regulator of Gz selective protein signaling 1,Regulator of Gz-selective protein signaling 1,RGS20,RGS20,RGSZ1,ZGAP1

Background: The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 44kDa

Calculated_MW: 17kDa/21kDa/25kDa/27kDa/31kDa/43kDa

Gene ID: 8601

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling