MGAT2 antibody

Catalog No. ABIN6571945

This anti-MGAT2 antibody is a Rabbit Polyclonal antibody detecting MGAT2 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for MGAT2 antibody (ABIN6571945)

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGAT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MGAT2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human MGAT2

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MGAT2

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Alternative Name: MGAT2

Background:

Synonyms: Alpha 1,6 mannosyl glycoprotein 2 beta N acetylglucosaminyltransferase,Beta 1,2 N acetylglucosaminyltransferase II,CDG2A,CDGS2,GlcNAc T II ,GLCNACTII,GNT II,GNT2,Mannoside acetylglucosaminyltransferase 2,N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase II,UDP N acetylglucosamine:alpha 6 D mannoside beta 1,2 N acetylglucosaminyltransferase II

Background: The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Molecular Weight:

Observed_MW: 60kDa

Calculated_MW: 51kDa

Gene ID: 4247

UniProt: Q10469