PCCA antibody

Catalog No. ABIN6571988

The Rabbit Polyclonal anti-PCCA antibody is suitable to detect PCCA in samples from Mouse and Rat. It has been validated for WB.

Quick Overview for PCCA antibody (ABIN6571988)

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCCA Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PCCA (NP_000273.2).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA

Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 75kDa/77kDa/80kDa

Gene ID: 5095

UniProt: P05165

Pathways: Monocarboxylic Acid Catabolic Process