TRIP12 antibody

Catalog No. ABIN6572095

This Rabbit Polyclonal antibody specifically detects TRIP12 in IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRIP12 antibody (ABIN6572095)

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP12 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-TRIP12 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TRIP12 (NP_001271143.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIP12

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Alternative Name: TRIP12

Background: The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.

Molecular Weight:

Observed_MW: 260kDa

Calculated_MW: 192kDa/220kDa/223kDa/225kDa

Gene ID: 9320

UniProt: Q14669

Pathways: Nuclear Hormone Receptor Binding