SGEF antibody (AA 378-406)

Catalog No. ABIN657248

The Rabbit Polyclonal anti-SGEF antibody has been validated for WB and IHC (p). It is suitable to detect SGEF in samples from Human.

Quick Overview for SGEF antibody (AA 378-406) (ABIN657248)

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGEF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33350

Product Details anti-SGEF Antibody

Binding Specificity: AA 378-406

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Alternative Name: SGEF

Background: SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

Molecular Weight: 97346

NCBI Accession: NP_001238891, NP_001238892, NP_056410

UniProt: Q96DR7