CCDC99 antibody (C-Term)

Catalog No. ABIN2846461

This Rabbit Polyclonal antibody specifically detects CCDC99 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CCDC99 antibody (C-Term) (ABIN2846461)

Target: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC99 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33449

Product Details anti-CCDC99 Antibody

Binding Specificity: AA 459-488, C-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCDC99 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of human CCDC99.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CCDC99 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for CCDC99

Target: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Alternative Name: CCDC99

Background: CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.

Molecular Weight: 70172

Gene ID: 54908

NCBI Accession: NP_060255

UniProt: Q96EA4