ITGAL antibody (AA 722-751)

Catalog No. ABIN657615

The Rabbit Polyclonal anti-ITGAL antibody (Clone RB33604) (ABIN657615) specifically detects ITGAL in WB. The antibody is reactive with Human samples.

Quick Overview for ITGAL antibody (AA 722-751) (ABIN657615)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB33604

Product Details anti-ITGAL Antibody

Binding Specificity: AA 722-751

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITGAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ITGAL.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ITGAL Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: ITGAL

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 128770

Gene ID: 3683

NCBI Accession: NP_001107852, NP_002200

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex