Galectin 3 antibody (C-Term)

Catalog No. ABIN657647

The Rabbit Polyclonal anti-Galectin 3 antibody has been validated for WB and IHC (p). It is suitable to detect Galectin 3 in samples from Human. There is 1 publication available.

Quick Overview for Galectin 3 antibody (C-Term) (ABIN657647)

Target: Galectin 3 (LGALS3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33695

Product Details anti-Galectin 3 Antibody

Binding Specificity: AA 167-196, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LGALS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-196 amino acids from the C-terminal region of human LGALS3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LGALS3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-Galectin 3 antibody (ABIN657647)

Rao, Tian, Ma, Yan, Thapi, Schultz, Rosales, Monette, Wang, Hyman, Levine, Solit, Spriggs: "Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion." in: PLoS ONE, Vol. 10, Issue 5, pp. e0126633, (2015) (PubMed).

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: LGALS3

Target Type: Chemical

Background: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Molecular Weight: 26152

Gene ID: 3958

NCBI Accession: NP_002297

UniProt: P17931

Pathways: RTK Signaling