RORC antibody (AA 187-216)

Catalog No. ABIN657708

The Rabbit Polyclonal anti-RORC antibody (Clone RB33929) (ABIN657708) specifically detects RORC in WB. The antibody is reactive with Human samples.

Quick Overview for RORC antibody (AA 187-216) (ABIN657708)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORC antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB33929

Product Details anti-RORC Antibody

Binding Specificity: AA 187-216

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RORC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human RORC.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RORC Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Alternative Name: RORC

Background: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 58195

Gene ID: 6097

NCBI Accession: NP_001001523, NP_005051

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway