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RLN1,RLN2 antibody (C-Term)

Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33916 unconjugated
Catalog No. ABIN657785
  • Target See all RLN1,RLN2 products
    RLN1,RLN2
    Binding Specificity
    • 7
    • 6
    • 6
    AA 136-165, C-Term
    Reactivity
    Human
    Host
    • 13
    • 2
    Rabbit
    Clonality
    • 13
    • 2
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This RLN1,RLN2 antibody is un-conjugated
    Application
    • 14
    • 13
    • 13
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RLN1/RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human RLN1/RLN2.
    Clone
    RB33916
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    RLN1/RLN2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    RLN1,RLN2
    Alternative Name
    RLN1/RLN2 (RLN1,RLN2 Products)
    Background
    Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet. [provided by RefSeq].
    Molecular Weight
    21146
    Gene ID
    6013
    NCBI Accession
    NP_008842
    UniProt
    P04808
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