Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HTR2C antibody (AA 253-282)

HTR2C Reactivity: Human WB Host: Rabbit Polyclonal RB34033 unconjugated
Catalog No. ABIN657817
  • Target See all HTR2C Antibodies
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    Binding Specificity
    • 15
    • 10
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 253-282
    Reactivity
    • 72
    • 44
    • 43
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 68
    • 3
    • 1
    Rabbit
    Clonality
    • 61
    • 11
    Polyclonal
    Conjugate
    • 34
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HTR2C antibody is un-conjugated
    Application
    • 58
    • 32
    • 14
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HTR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the Central region of human HTR2C.
    Clone
    RB34033
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HTR2C Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    HTR2C Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    Alternative Name
    HTR2C (HTR2C Products)
    Synonyms
    5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-HT2cR antibody, 5HT1c antibody, Htr1c antibody, SR1 antibody, 5HT-1C antibody, 5HT2C antibody, 5-HT-2C antibody, 5-ht2cr antibody, si:dkey-24g18.2 antibody, 5ht2c antibody, 5HTR2C antibody, 5-hydroxytryptamine receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody, HTR2C antibody, Htr2c antibody, htr2c.S antibody, htr2cl1 antibody, LOC407134 antibody
    Background
    Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims.
    Molecular Weight
    51821
    Gene ID
    3358
    NCBI Accession
    NP_000859, NP_001243689, NP_001243690
    UniProt
    P28335
    Pathways
    Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
You are here:
Support