ABL1 antibody (AA 613-641)
Quick Overview for ABL1 antibody (AA 613-641) (ABIN657828)
Target
See all ABL1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Binding Specificity
- AA 613-641
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- WB: 1:1000. IHC-P: 1:10~50
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Mouse Abl1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
-
Expiry Date
- 6 months
-
-
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
-
Alternative Name
- Abl1
-
Background
- Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
-
Molecular Weight
- 122673
-
Gene ID
- 11350
-
NCBI Accession
- NP_001106174, NP_033724
-
UniProt
- P00520
-
Pathways
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
Target
-