HPSE antibody (AA 241-290)

Catalog No. ABIN6579223

This Rabbit Polyclonal antibody specifically detects HPSE in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HPSE antibody (AA 241-290) (ABIN6579223)

Target: HPSE (Heparanase (HPSE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPSE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-HPSE Antibody

Binding Specificity: AA 241-290

Purpose: HPA1 Antibody

Specificity: HPA1 Polyclonal Antibody detects endogenous levels of HPA1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human HPSE. AA range:241-290

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HPSE

Target: HPSE (Heparanase (HPSE))

Alternative Name: HPSE

Background:

Synonyms: HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1, Heparanase, Endo-glucoronidase, Heparanase-1, Hpa1

Background: Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix.The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Gene Name: HPSE

Protein Name: Heparanase

Molecular Weight: 61 kDa

Gene ID: 10855

OMIM: 604724

UniProt: Q9Y251

Pathways: Glycosaminoglycan Metabolic Process