BNIP3 antibody (AA 71-120)

Catalog No. ABIN6579229

The Rabbit Polyclonal anti-BNIP3 antibody is suitable to detect BNIP3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF and ELISA.

Quick Overview for BNIP3 antibody (AA 71-120) (ABIN6579229)

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BNIP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-BNIP3 Antibody

Binding Specificity: AA 71-120

Purpose: BNIP-3 Antibody

Specificity: BNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BNIP3. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BNIP3

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Alternative Name: BNIP3

Background:

Synonyms: BNIP3, NIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Background: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],

Gene Name: BNIP3

Protein Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Molecular Weight: 21 kDa

Gene ID: 664

OMIM: 603293

UniProt: Q12983

Pathways: Autophagy, Brown Fat Cell Differentiation